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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AADAC
All Species:
23.64
Human Site:
S259
Identified Species:
52
UniProt:
P22760
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22760
NP_001077.2
399
45748
S259
E
Y
F
T
T
D
R
S
L
E
K
A
M
L
S
Chimpanzee
Pan troglodytes
XP_516822
399
45724
S259
E
Y
F
T
T
D
R
S
L
E
K
A
M
L
S
Rhesus Macaque
Macaca mulatta
XP_001106694
399
45806
S259
E
Y
F
T
T
D
R
S
L
E
K
A
M
L
S
Dog
Lupus familis
XP_534309
399
45879
S259
E
Y
F
T
V
D
K
S
L
V
K
A
M
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99PG0
398
45232
G258
E
Y
F
T
T
D
R
G
L
E
K
A
M
L
L
Rat
Rattus norvegicus
Q9QZH8
398
45674
D258
E
Y
F
T
T
D
R
D
L
E
K
A
M
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505353
290
33323
D160
S
N
R
H
V
P
V
D
S
S
H
L
F
K
F
Chicken
Gallus gallus
XP_422836
403
44590
S259
E
Y
F
T
S
D
P
S
L
R
E
A
I
T
S
Frog
Xenopus laevis
NP_001104216
403
45798
T259
E
Y
I
T
T
D
R
T
L
G
E
A
M
W
H
Zebra Danio
Brachydanio rerio
XP_001923714
410
46788
S262
E
Y
F
T
S
D
K
S
F
L
R
A
M
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LYC1
358
40281
Q228
F
G
G
Q
E
R
T
Q
S
E
K
T
L
D
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
92.4
75.6
N.A.
69.6
67.6
N.A.
50.8
57
54.8
48.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
94.9
85.7
N.A.
84.2
83.4
N.A.
60.6
77.9
71.2
66.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
0
60
60
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
86.6
86.6
N.A.
0
80
73.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
82
0
19
0
0
0
0
0
10
0
% D
% Glu:
82
0
0
0
10
0
0
0
0
55
19
0
0
0
0
% E
% Phe:
10
0
73
0
0
0
0
0
10
0
0
0
10
10
10
% F
% Gly:
0
10
10
0
0
0
0
10
0
10
0
0
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
10
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
19
0
0
0
64
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
73
10
0
10
10
46
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
73
10
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
10
55
0
0
10
10
0
0
0
0
% R
% Ser:
10
0
0
0
19
0
0
55
19
10
0
0
0
0
46
% S
% Thr:
0
0
0
82
55
0
10
10
0
0
0
10
0
10
0
% T
% Val:
0
0
0
0
19
0
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
82
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _